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Akeo, Kiyoshi*; Funayama, Tomoo; Kobayashi, Yasuhiko; Akeo, Yoko*
JAEA-Review 2014-050, JAEA Takasaki Annual Report 2013, P. 80, 2015/03
It is known that superoxide dismutases (SOD) are a class of enzymes that catalyze the dismutation of superoxide into oxygen and hydrogen peroxide. Ionizing radiation is known to induce oxidative stress through generation of reactive oxygen species resulting in imbalance of the pro-oxidant and antioxidant in the cells, which is suggested to culminate in cell death. Therefore, we measured the activity of SOD in human RE cells exposed to the He- and C-ion beam. The cells collected at 0, 4, 8, and 24 hr after irradiation were extracted by adding the SOD assay buffer to the pellets, and lysed by several cycles of freezing and thawing. The activity of SOD was measured using a modification of the luminol assay. SOD activity decreased according to duration time after irradiation of He-ion, however, in case of C-ion, it increased at 24 hr after irradiation. The result suggested that that there were the differences of the effects by irradiation on SOD activity between He- and C-ion.
Mizuhashi, Kiyoshi; Uno, Sadanori; Okoshi, Kiyonori; Chiba, Atsuya; Saito, Yuichi; Ishii, Yasuyuki; Sakai, Takuro; Tajima, Satoshi
Dai-17-Kai Tandemu Kasokuki Oyobi Sono Shuhen Gijutsu No Kenkyukai Hokokushu, p.5 - 8, 2004/00
The three electrostatic accelerators were smoothly operated according to an allotted beam time. The total operation time for each accelerator in FY 2003 was 1,988 hours for the tandem accelerator, 2,286 hours for the single-ended accelerator and 1,773 hours for the 400kV ion implanter, respectively. The difference in the operating time between these accelerators dependent on the complexity of the ion source and the generating the quantities of ion species. And present state of 3MV tandem accelerator is reported.
Tu, Z.; Kobayashi, Yasuhiko; Kiguchi, Kenji*; Watanabe, Hiroshi
Nuclear Instruments and Methods in Physics Research B, 206, p.591 - 595, 2003/05
no abstracts in English
Matsuda, Makoto; Takeuchi, Suehiro; Yoshida, Tadashi; Hanashima, Susumu; Fujii, Yoshio*
Dai-14-Kai Kasokuki Kagaku Kenkyu Happyokai Hokokushu, p.170 - 172, 2003/00
no abstracts in English
Matsuda, Makoto; Fujii, Yoshio*; Tayama, Hidekazu; Ishizaki, Nobuhiro; Abe, Shinichi; Hanashima, Susumu; Tsukihashi, Yoshihiro; Horie, Katsuzo; Ouchi, Isao; Kanda, Susumu; et al.
JNC TN7200 2001-001, p.166 - 168, 2002/01
no abstracts in English
Arakawa, Kazuo
Hoshasen Kagaku, (65), p.44 - 46, 1998/00
no abstracts in English
Arakawa, Kazuo
Hoshasen To Sangyo, (75), p.37 - 38, 1997/00
no abstracts in English
Fukuda, Mitsuhiro; Arakawa, Kazuo; Okumura, Susumu; Nakamura, Yoshiteru; Nara, Takayuki; Agematsu, Takashi; Ishibori, Ikuo; Yokota, Wataru; Tamura, Hiroyuki
Proc. of 11th Symp. on Accelerator Sci. and Technol., p.139 - 141, 1997/00
no abstracts in English
Namba, Hideki
Shitsuryo Bunseki, 43(5), p.313 - 322, 1995/00
no abstracts in English
Onuki, Toshihiko; D.E.Robertson*
Materials Research Society Symposium Proceedings, Vol. 176, p.615 - 622, 1990/00
None
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Kagaku To Kogyo, 36(9), p.160 - 162, 1983/00
no abstracts in English